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Upon ligand binding, TβR II phosphorylates and activates TβR I, forming a heteromeric receptor complex that initiates downstream signaling through both SMAD-dependent and SMAD-independent pathways, such as ERK, p38, JNK, and PI3K-Akt cascades [33, 36, 39]
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Chemical purity:>99%
doi: 10.3390/ijms24021476
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