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https://lookaside.fbsbx.com/lookaside/crawler/media/?media_id=943930617977637 Reactive oxygen species (ROS) produced by UVR, detectable within 15 min of exposure, stimulate release of proinflammatory cytokines and growth factors that disrupt skin's structural integrity: AP-1 and NFκB increase production of matrix metalloproteinases that break down extracellular matrix collagen and elastin fibers, and TGF-β decreases production of collagen (Figure 6) size:30 g bearenger petrella Aneuploidy selects for the acquisition of driver genes in breast cancer | Nature

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