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Disruption of GH and IGF1 signaling extends lifespan, enhances insulin sensitivity, decreases DNA and protein oxidation in the liver, reduces cancer incidence and may reduce age-related inflammation

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Postprandial Hyperglycemia Leads to Activation of Inflammatory Pathways Postprandial hyperglycemia increases inflammation in humans, as indicated by an increase in high-sensitivity C-reactive protein [103,104]