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As previously shown 26 , recombinant AT-1002, the active domain of Vibrio cholerae’s zonula occludens toxin (ZOT, zonulin) on average tended to decrease the transepithelial electrical resistance (TEER) in Caco-2 cell monolayers, indicating the permeability of epithelial cell monolayers (Fig
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Despite the relative closeness in age, the PCA plot revealed that p14 and p28 transcriptomes could be easily separated (Figure 7A), with 851 DEGs between p14 and p28 AF tissue with roughly half of these genes significantly higher in the p28 and half significantly lower (Figure 7B)
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