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Results Disulfiram has anticancer effects against neuroblastoma cell lines in the nanomolar range We tested the anticancer effects of disulfiram in four neuroblastoma cell lines with MYCN amplification (IMR-32, SK-N-DZ, SJ-N-TQ-24 and IGR-N91, hereafter named N91) and two without (SK-N-AS and SK-N-SH

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328 ADI-PEG-20, in combination with pemetrexed and cisplatin (ADIPEMCIS), was well tolerated in another phase I study of recurrent high-grade glioma (HGG) (NCT02029690)