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This signaling pathway has been shown to be compromised by Aβ both in vitro , using oligomeric Aβ treated cultured neurons or brain slices, and in vivo as evidenced by Aβ overproducing transgenic AD mouse models (Vitolo et al., 2002
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MEA Tested:No
doi: 10.1016/j.fsi.2014.07.017 155
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