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(Ludwig KA) Ann Surg Oncol 2011 Jun;18(6):1520-1 2 Sudden cardiac death resulting from acute coronary artery aneurysm occlusion: successful resuscitation and treatment of an adolescent boy with previously unrecognized Kawasaki disease

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The phagocyte NADPH oxidase, when activated, generates quantities of O 2 •− and H 2 O 2 accounting for a significant fraction (10–90%) of total oxygen consumption of neutrophils, macrophages, and microglia, but the contribution of such and other NADPH oxidases to total cellular ROS production in resting or during activation is less clear [23]