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Significant Changes in Circulating Monocyte Subsets in COVID-19 Patients Human blood monocytes are bone marrow-derived cells that circulate in the blood for 1–3 days, and during this time undergo a process of maturation from classical CD14 high CD16 − monocytes (also referred as inflammatory monocytes) into non-classical CD14 low CD16 + group (also known as patrolling monocytes) through the generation of an intermediate monocyte subset (CD14 high CD16 + ) (55, 56)

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10.1186/s13048-026-02007-y 113 WeiX.ShiJ.LinQ.MaX.PangY.MaoH.et al (2021)