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However, when the blood supply to the brain is insufficient, the end result is dizziness and lightheadedness, especially when the patient stands up suddenly or exerts themselves
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As examples, the phosphorylated ubiquitin at serine 65 and the kinase Nek7 at serine 195, which are artificially activated by genetically encoded pSer, can respectively activate Parkin E3 ligase activity, and robustly phosphorylate myelin basic protein (MBP) as well as bypass activation by the C-terminal domain of Nek9 (Nek9-CTD) in vitro
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