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10.1615/jenvironpatholtoxicoloncol.2014010606 J
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FIGURE 3 4.2.1 DNA methylation and drug metabolism DNA methylation is one of the most important mechanisms that is influencing gene expression that is involves adding a methyl group to cytosine residues specifically at CpG sites that is commonly found in gene promoter sequences, and this addition is maintained by variety of DNA methyltransferases enzymes (DNMTs) (Rushing et al., 2023)
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