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For example, in Saccharomyces cerevisiae , Cu-mediated damage to the labile Fe–S pool in mitochondrial ferredoxin leads to downstream growth inhibition
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Cross-talk between amylin receptor pathways and GLP-1 receptor downstream effectors, particularly at the level of PI3K/Akt and MAPK signalling, is an active area of mechanistic investigation using cagrilintide as a research probe
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