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✓ The FDA has repeatedly flagged AOD-9604 as a compound of concern. It was placed on the Category 2 list in 2023 — bulk drug substances in compounding that may present significant
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Am J Physiol Endocrinol Metab , 2000 β3-AR knockout mice lose the chronic weight-loss response but retain acute fat oxidation — so there's a β3-independent lipolytic signal running in parallel, with β3 upregulation doing most of the long-term work
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