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The plasma level of anti-Tat IgG1 (typical of Th2 response) as well as the levels of anti-Tat IgG2a and IgG2b measured by ELISA assay were lowered and increased, respectively, among Tat-immunized mice pretreated with GSH-C4 or I-152, implying the Th1 response [66,70,91]
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