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NNMT’s role is to transfer a methyl group to nicotinamide (vitamin B3), creating 1-methylnicotinamide — a reaction that consumes cellular methyl donors and depletes nicotinamide adenine dinucleotide (NAD⁺) stores

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[Google Scholar] 21.Puissant A, Vanbremeersch F, Monfort J, Lamberton JN, [A new iatrogenic dermatosis: acne caused by vitamin B 12]