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Symptoms related to a lack of vitamin B12 include: Extreme tiredness Shortness of breath Nervous system issues, including numbing sensations or pins and needles Muscle weakness that may cause trouble walking and uncontrolled movements Mouth ulcers Sore tongue Neurological and psychiatric problems, including irritability, depression, confusion, changes in personality, depression, anxiety, and memory loss Vision problems Lack of energy Digestive issues, including nausea, vomiting, diarrhea, loss of appetite, or indigestion The Benefits of Getting Our B12 Shots in St