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The nitrogen-containing cyclopropane monoethanolamine-functionalized gold nanoparticles (Au-MEA NPs) prepared by the ligand exchange method using citric acid-terminated gold nanoparticles (Au-CA NPs) can effectively alleviate psoriasis-like and rosacea-like chronic skin inflammation by promoting SOD activity and inhibiting MMP9 activity, thereby reducing the generation of pro-inflammatory mediators in keratinocytes (Zhao et al., 2024)

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In the pathogenesis of this disease, the interplay among the genes, intrinsic, and extrinsic factors are crucial