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BPC 157 showed effectiveness over the NO-system background, immobilized (L-NAME + L-arginine), (over)stimulated (L-arginine) or blocked (L-NAME)

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RT-qPCR of mouse dorsal skin after treatment further confirmed the upregulation of IGF-1, VEGF, Elastin, and HAS2, while the downregulation of TNF-α and IL-1β