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This may be essential for the penetration of both the epineurium and neuronal membrane, during the action, for the time that a local anesthetic remains in close proximity to neural fibres, since lidocaine shortens its own duration by dilating local vasculature [46]
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The expression of NtMEK2 DD induced the generation of hydrogen peroxide and up-regulated the expression of defense-related genes including PR- genes, peroxidases and GSTs including GSTTU4 and GSTTU12 (Jeong et al., 2008)
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