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However, both conditions often share common underlying causes, including low-fibre diets, physical inactivity, and metabolic dysfunction, which explains why they frequently occur together in the same individuals
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Furthermore, more recently glycoprotein E (gE) has also been reported to act as an inhibitor of apoptosis in epithelial cells, which was achieved by triggering ERK1/2 activation and was associated with the degradation of the pro-apoptotic protein Bim (Figure 2A
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