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Methylcobalamin plus a corticosteroid helped patients recover faster than a corticosteroid alone in a study of subjects who had Bell’s palsy longer than two weeks

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The pooled safety analysis of four placebo-controlled trials — two phase 2 and two phase 3, 1,997 patients who received at least one dose at 75 to 260 units — put neck pain at 12.6%, muscle weakness at 8.0%, musculoskeletal stiffness at 6.1%, and ptosis at 4.6% of treated patients, serious adverse events at 5.4% versus 3.0% on placebo, and discontinuation for an adverse event at 3.4% (Diener 2014)