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Peptides that modulate protein–protein interactions may be rationally developed by mimicking one of the two partners involved in a protein–protein interaction [341], or directly derived from the screening of peptide sequences that do not originate from natural proteins [342]
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SNAP-8# Evidence Level: In vitro and clinical cosmetic studies | FDA Status: Cosmetic ingredient SNAP-8 (acetyl octapeptide-3) inhibits SNARE complex formation at the neuromuscular junction, reducing muscle contraction intensity
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