precursor of glutathione Improving production by engineered Pichia pastoris: strain construction and optimal feeding GMP certified.

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The elucidation of the molecular principles of oxygen-sensing which control Epo production, notably the HIF-PHD-VHL interplay, in the last few years (Nobel Prize 2019) has led to the development of novel oral PHD inhibitors as a potential alternative to the expensive Epo supplementation to treat anemic CKD patients, though a better understanding of the renal oxygen-signaling pathway becomes even more crucial [123]

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