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In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds Maquart FX, Bellon G, Chaqour B, et al
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The elevated lactate microenvironment induces the lactylation of METTL3 protein, increasing m6A methylation on TFRC mRNA, accelerating cellular iron uptake, leading to Fe2+ accumulation, elevated ROS and malondialdehyde levels, and ultimately inducing ferroptosis (77,94)
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