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Conversion of extracellular NMN to NR mediated by enzyme CD73 is required for cell uptake and intracellular synthesis of NAD+ (Ratajczak et al., 2016)

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This has naturally created interest in whether 5-Amino-1MQ could eventually become useful for people struggling with: stubborn body fat metabolic dysfunction difficulty improving body composition age-related changes in metabolism fat accumulation despite lifestyle interventions However, a promising mechanism is not the same as a proven clinical treatment